Sodium bis(trimethylsilyl)amide 1M THF;NAHMDS
1.Molecular Formula: C6H18NNaSi2
2.Molecular Weight: 183.37
3.CAS NO.: 1070-89-9
4. Purity：Min 97%
Description
| Index | Standard |
|---|---|
| Appearance | Colorless to pale yellow solution |
| Concentration | 1.0M (±0.05M) in THF |
| Purity (NaHMDS) | ≥97.0% |
| Water Content | ≤0.1% |
Properties: Sodium bis(trimethylsilyl)amide
- Chemical Nature: Strong, moisture-sensitive base in an anhydrous THF solution
- Reactivity: Highly reactive with H₂O/O₂ – must be handled under inert atmosphere (N₂/Ar)
- Solubility: Fully miscible with most organic solvents (ethers, hydrocarbons)
Applications:
- Organic Synthesis: Preferred base for enolate formation；Deprotonation of weakly acidic C-H bonds；Anionic polymerization initiator
- Pharmaceuticals: Critical reagent for β-lactam antibiotic synthesis；Used in nucleoside modifications
- Materials Science: Precursor for silicon nitride CVD；Surface silylation agent
Package & Storage:
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- 100mL/500mL/1L bottles
