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Hydroxypropyl Chitosan: New Possibilities in Biotech and Materials Science

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As industries worldwide seek safer, more sustainable, and biocompatible solutions, Hydroxypropyl Chitosan emerges as a versatile material bridging medicine, biotechnology, and advanced manufacturing. From wound healing and tissue engineering to drug delivery and even paper enhancement, this functional biopolymer is unlocking new opportunities for innovation.

Hydroxypropyl Chitosan Information

Product Name: Hydroxypropyl Chitosan (Pharmaceutical Grade)
Synonym: Hydroxypropyl Deacetylated Chitosan
Molecular Formula: (C6H11NO4)m(C3H6O)n  m = degree of polymerization; n = degree of substitution
CAS No.: 104673-29-2
Cosmetic Ingredient Submission Code: 005251-12444-5653

羟丙基chitosan
                   Hydroxypropyl Chitosan 

Hydroxypropyl Chitosan Standards

Testing Standard: In-house Specification

Test Item Specification
Appearance Off-white to light brown amorphous or crystalline powder
Solution Clarity Clear solution
pH Value 6.0 – 9.0
Kinematic Viscosity 1 – 10 mm²/s
1,2-Propylene Glycol ≤ 0.50%
Loss on Drying ≤ 10.0%
Residue on Ignition ≤ 5.0%

Hydroxypropyl Chitosan Applications

Hydroxypropyl Chitosan features excellent biological activity, biocompatibility, biodegradability, and immune-enhancing properties, making it suitable for a wide range of fields:

  • Antimicrobial Effect:
    The —NH₂ groups in Hydroxypropyl Chitosan can form —NH₃⁺ in acidic solution, which interacts with negatively charged cell walls, altering permeability and thereby inhibiting or killing microbes.

  • Wound Healing & Dressings:
    It degrades in the body to produce N-acetylglucosamine, which promotes fibroblast proliferation, collagen deposition, and natural hyaluronic acid synthesis, accelerating wound healing.

  • Drug Delivery & Adsorption:
    Through electrostatic interaction, Hydroxypropyl Chitosan binds with negatively charged proteins or plasmid DNA. Combined with nanoparticle technology, it serves as an effective drug delivery carrier.

  • Tissue Engineering:
    Crosslinking Hydroxypropyl Chitosan with gelatin and chondroitin sulfate produces a transparent scaffold with enhanced cell compatibility, supporting corneal cell adhesion and proliferation.

  • Paper Industry:
    Improves tensile strength, folding endurance, and resistance to dry-heat aging, enhancing overall paper durability.

Packaging & Storage

Packaging: Complies with pharmaceutical packaging standards
Available Sizes: 0.1kg/bag, 1kg/bag, 2kg/bag, 10kg/bag/drum, 20kg/bag/drum
Storage: Store in a sealed container, protected from light

With its pharmaceutical-grade quality, proven biological activity, and multifunctional applications, Hydroxypropyl Chitosan is more than just a material—it’s a solution driving progress across healthcare, biotechnology, and sustainable industries.

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